Lupus Society of Alberta

NORMAL IMMUNE SYSTEM
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What might be happening in someone who has lupus ...
#1 Possibility:

  • B-Cell produces too many antibodies
  • T-Helper Cell sends too many signals
#2 Possibility:

  • B-Cell ignores signal from the T-Suppressor cell to stop making antibodies
#3 Possibility:

  • The line is scrambled so the 'stop' signal doesn't get through
During a lupus flare ...
Uncontrolled antibodies in the person with lupus attack the connective tissue of the body.

This results in:
  • direct damage to cells in many systems of the body
  • inflammatory reactions caused by immune complexes which the body is unable to eliminate